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Chocolate is good for the heart, page 4 of 5

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The study selection

The following kinds of studies were selected: randomized trials and cohort, case-control, and cross sectional studies carried out in human adults, in which the association between chocolate consumption and the risk of outcomes related to cardiometabolic disorders were reported.

The data extraction

Data were extracted by two independent investigators, and a consensus was reached with the involvement of a third. The primary outcome was cardiometabolic disorders, including cardiovascular disease (coronary heart disease and stroke), diabetes, and metabolic syndrome. A meta-analysis assessed the risk of developing cardiometabolic disorders by comparing the highest and lowest level of chocolate consumption.

The results

From 4576 references, seven studies met the inclusion criteria (including 114,009 participants). None of the studies was a randomized trial, six were cohort studies, and one was a cross sectional study. Large variation was observed between these seven studies for the measurement of chocolate consumption, methods, and outcomes evaluated. Five of the seven studies reported a beneficial association between higher levels of chocolate consumption and the risk of cardiometabolic disorders. The highest levels of chocolate consumption were associated with a 37% reduction in cardiovascular disease (relative risk 0.63 (95% confidence interval 0.44 to 0.90)) and a 29% reduction in stroke compared with the lowest levels.

The conclusion

Further experimental studies are required to confirm a potentially beneficial effect of chocolate consumption.

However, based on observational evidence, levels of chocolate consumption seem to be associated with a substantial reduction in the risk of cardiometabolic disorders. In other words, scientific study confirms that chocolate is good for the heart! (1)   ...More >>

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