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How to treat vitamin D deficiency, page 2 of 7

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But isn't it too much?

Thanks to the government's manipulation of numbers, the question arises: "Isn't your recommended dose too large?" No, it's not. Why?

Take 20,000 IU because you've got nothing to lose. You will likely regain your health, if you take daily doses of up to 20,000 IU. FYI, no toxicity has ever been reported under 20,000 IU per day.

Take 15,000 IU. Take 15,000 IU per day. 15,000 IU per day is still pretty safe (for up to six months).

Take 10,000 IU. Your plasma vitamin D level might be so low that you might need to take 10,000 IU (or even more) per day (for up to six months) in order to bring your plasma vitamin D level up to normal.

Take 10,000 IU. If your skin doesn't get exposed to the sun, it's reasonable to take up to 10,000 IU per day, in order to bring your plasma vitamin D level up to normal.

Take 10,000 IU. If you're on a low-fat diet, it's especially reasonable to take up to 10,000 IU per day, in order to bring your plasma vitamin D level up to normal.

Take 5,000 IU. 5,000 IU is so small that it's unbelievable! 125 mcg is only 125 millionth of one gram!

Take 4,000 IU. Your plasma level of vitamin D should be between 50 and 65 ng/mL (125 and 162.5 nmol/L), which requires that you take, for the rest of your life, the very minimum of 4,000 IU per day, every day.

Scientists are getting increasingly more aware that new and higher (than current) cut-off levels are needed. The issue is that, in the past, scientists used wrong statistical approaches for defining "normal serum 25(OH)D levels". In agreement with this new classification, in a recent study, conducted in a random sample of our population, a high prevalence of low levels of 25(OH)D and secondary hyperparathyroidism was found. (6)

In the study, only in those people having "excellent" renal function, representing only 15% of the sample (serum creatinine less than 1 mg/dl in men and less than 0.8 in women, mean age of 68 years) hyperparathyroidism was not diagnosed despite observing 25(OH)D serum levels around 18-30 ng/ml or 45-75 nmol/l). (6)

In the remaining people (85% of the sample) who showed the expected serum creatinine increments according to their age, secondary hyperparathyroidism was avoided, only if the serum 25(OH)D levels were higher than 30 ng/ml or 75 nmol/l. These remarkable findings demonstrate the importance of maintaining higher 25(OH)D levels — in addition to normal calcitriol levels — in order to avoid stimulation of the parathyroid gland. (6)

Take 10,000 IU. Lifeguards have 250 nmol/L plasma levels without any toxicity. In one scientific study, healthy young men receiving up to 10,000 IU (250 mcg) per day for 20 weeks didn't show any toxicity at all. (5)

Take 20,000 IU. This level of vitamin D supplementation may sound like a lot. However it's still modest and still very safe because no toxicity has ever been reported under 20,000 IU per day. ...More >>

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